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Monkeypox is a rare viral infection that causes a high temperature (fever) and a body rash lasting a few weeks. It mainly occurs in remote parts of central and west Africa.

Recommendations for Travellers

Monkeypox is very rare in travellers to Africa. Prior to 2022 it mainly occurred in remote parts of central and west Africa when a person had contact with animals infected with monkeypox. Occasionally the infection then spread to someone else in the person’s house.

In 2022, monkeypox has been reported in people in the UK, Europe and other international countries. 

Generally, there is a low risk of becoming infected with monkeypox during travel. The risk is greater if you have close contact, including during sex, with a person who has the infection and who has symptoms.

If you are travelling to central or west Africa you should:

  • avoid contact with monkeys and rodents (for example rats, mice, squirrels) and avoid eating undercooked meat from these animals
  • wear protective clothing, including gloves, if you are involved in the slaughter of, or care of animals
  • practice careful hand hygiene if visiting or caring for ill friends and relative

If you plan to be sexually active during travel to any destination, you should:

  • practise safe sex
  • avoid close, including sexual contact, with someone who is unwell and may have monkeypox

You should seek medical advice during, and for 21 days after travelling if you develop symptoms of monkeypox and:

  • you have returned from west or central Africa
    • you should also ensure you are checked for malaria


  • you have had close contact with someone who may have monkeypox

For further information see:

There is no vaccine to protect against monkeypox, but previous smallpox vaccination offers some protection.   

Overview of the Disease

Monkeypox is caused by the monkeypox virus. It does not spread readily between people.

Some animals in Africa, including rodents (rats, mice and squirrels) can carry the infection.

Infection can be caught from:

  • infected animals in west and central Africa
    • close contact with infected animals including touching them or eating their undercooked meat increases your risk


  • close contact with a person with monkeypox from their:
    • rash (having skin contact, including during sex)
    • clothes, bedding, towels or personal items
    • coughs or sneezes

The Illness

After becoming infected, symptoms usually start 5 to 21 days later and usually get better by themselves over a few weeks.

First symptoms include:

  • high temperature (fever)
  • headache
  • flu-like symptoms, including muscle and back aches, shivering and tiredness
  • swollen glands (in the neck, armpits or groin)

A blistering rash starts 1 to 5 days after the other symptoms. It may start on the face or in the genital areas and then may spread to the rest of the body

The rash changes from raised spots to blisters and then scabs, similar to a chickenpox rash.


There is no specific treatment for monkeypox and it usually gets better by itself. Medicines that help pain, fever and discomfort from the rash can be given.

People with monkeypox should stay isolated from others to ensure they can’t pass on the infection.

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